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ConsLimited to Windows onlyPlatform Availability: WindowsInstall: Website (Free)SEE ALSO: 8 Best Windows Photo Viewer Alternatives for Windows 10 in 2019Which Rufus Alternative Did You PickSo that was our list of 10 best Rufus alternatives for all major operating systems and file formats. We have tried to include all the use-case scenarios so that you can easily create a bootable USB drive from any operating system and without any limitations. One thing we have kept common in all the alternatives is that the flashing speed is top-notch which is a distinct feature of Rufus. So that will be all from our side. If you liked our selection, do let us know in the comment section below.(adsbygoogle = window.adsbygoogle []).push({});TAGSLinuxmacOSRufusWindows10 Comments var adpushup = window.adpushup = window.adpushup {};adpushup.que = adpushup.que [];adpushup.que.push(function() {adpushup.triggerAd(\"7900abb6-e703-47f5-a47a-0b46ff86661d\");}); var adpushup = window.adpushup = window.adpushup {};adpushup.que = adpushup.que [];adpushup.que.push(function() {adpushup.triggerAd(\"684b976f-5367-4a76-8a1a-d90a2f380ed9\");});You Might LikeHow ToHow to Install Drivers in UbuntuHow ToHow to Install Python in Ubuntu Linux (4 Methods)How ToHow to Install Deb Files on Ubuntu Linux (4 Methods)How ToHow to Install Google Chrome on UbuntuHow ToHow to Check Your Ubuntu Version (4 Methods) var adpushup = window.adpushup = window.adpushup {};adpushup.que = adpushup.que [];adpushup.que.push(function() {adpushup.triggerAd(\"81026fc2-d37a-46ca-b79a-9321e405645e\");});Recommended ArticlesWhatsApp Beta for macOS Is Now Available for Everyone to TryHow to Fix Roblox Not Updating on Mac (8 Methods)How to Make Windows Look Like Mac (2 Methods)How to Take a Screenshot in Ubuntu (5 Easy Ways)How to Switch Between Wayland and Xorg in Ubuntu8 Best Screen Recorders For Linux10 CommentsKrystian Broniszewski says:Oct 25, 2020 at 9:15 pmI tested all avaiable software to linux. all dont work. only rufus on windows working good! all other is crashed!
Correlation analyses of metabolite abundances with antifungal activities indicated putative antifungal activities of four O-methylated flavones (18, 20, 25, 26), two flavanones (27, 28), and two dihydroflavonols (31, 32). In bioassay-guided fractionation, various O-methylated flavones were present in subfractions with moderate and high antifungal activity. In particular, the yet uncharacterized di-O-methylated and tri-O-methylated flavones (25, 26) from subfractions 4-1 and 4-3 showed promising activities against F. culmorum and B. cinerea. Naringenin (27), eriodictyol (28), and dihydrokaempferol (31) were the major constituents of fraction 3, which was not further fractionated during the bioassay-guided fractionation. Possibly, these three flavonoids could be responsible for the moderate antifungal activity of this fraction. The antifungal activities of some of the identified flavonoids are well-documented in the literature. Naringenin and dihydrokaempferol showed moderate antifungal activity against Candida albicans and Cryptococcus neoformans [23]. In maize, the biosynthesis of non-O-methylated and O-methylated flavones, flavanones, and dihydroflavonols is stimulated in the leaves upon infection with Bipolaris maydis [24]. The antifungal activity of selected representatives, such as naringenin, genkwanin, and xilonenin against the plant pathogens Fusarium graminearum, Fusarium verticillioides, and Rhizopus microspores has been demonstrated [24]. Similarly, sakuranetin (7-O-methylnaringein), detected in subfraction 4-4 with moderate activity against Fusarium culmorum, is a major phytoalexin in rice accumulating in blast-infected leaves and was shown to effectively inhibit spore germination of Pyricularia oryezae [25].
The bioassay-guided fractionation revealed other potential antifungal metabolites that were not highlighted by correlation analyses. Although hispidulin (19-1) and chrysoeriol (19-2) showed negative correlations between abundance and antifungal activity, they were present together with apigenin (1) in subfraction 4-2, which showed good antifungal activity against F. culmorum. Similarly, genkwanin (17) and sakuranetin (29) were detectable in the moderately active subfractions 4-7 and 4-4, respectively, but showed no significant correlations between abundance and antifungal activity. Previous studies have demonstrated the antifungal activities of hispidulin against B. cinerea [31], of chrysoeriol against Fusarium graminearum and Pythium graminicola [32], and of genkwanin against Fusarium verticillioides and Rhizopus microsporus [24]. It is therefore likely that these compounds also contribute to the antifungal activity of the hydroethanolic leaf extracts of Z. multiflora. In general, bioactive phenolic and flavonoid compounds can prevent fungal growth by inhibiting cell wall formation, cell division, and RNA and protein synthesis [33]. However, the bioactivity of a crude plant extract is a complex trait determined by the specific activities and absolute concentrations of a number of bioactive metabolites. It can additionally be influenced by synergistic effects that cannot be resolved even by bioassay-guided fractionation. Often bioactive metabolites are biosynthetically related to each other, so their accumulation in plant tissue is co-regulated. Based on a diverse set of crude plant extracts with contrasting antifungal activities, correlation analyses can reveal such relationships and accelerate the discovery of antifungal metabolites. However, correlation approaches are always only a first step in identifying bioactive metabolites and cannot replace fractionation approaches and bioassays in providing causative evidence for the bioactivity of a fraction of a crude plant extract or a purified metabolite. 1e1e36bf2d